How it Works

Polygiene® contains silver, a powerful antimicrobial agent proven to destroy viruses, bacteria and fungi.

Silver is a scientifically proven anti-microbial agent.

Silver ions released from Polygiene actively kill microbes long after application and does not evaporate like typical antibacterial products.

Silver is a scientifically proven anti-microbial agent.

Biochemical properties of silver in the ionic form, against pathogens like bacteria, virus, fungi and protozoa have been widely studied and the reaction products silver may produce are less harmful compared to other disinfectants which produce disinfection by-products (DBPs)

 

Mechanism of action

The antibacterial action of silver is dependent on the silver ion. The effectiveness of silver compounds as an antiseptic is based on the ability of the biologically active silver ion (Ag+) to irreversibly damage key enzyme systems in the cell membranes of pathogens via the oligodynamic effect,

Via this effect, the metabolism of bacteria is adversely affected by silver ions at concentrations of 0.01–0.1 mg/L. Therefore, even less soluble silver compounds, such as silver chloride, also act as bactericides or germicides.

The oligodynamic effect of silver ions

1. Silver ions perforate the peptidoglycan cell wall. 2. Silver ions then inhibit the cell respiration cycle.3. Metabolic pathways are also inhibited when in contact with silver. 4. Replication cycle of the cell is disrupted by silver particles via interaction with DNA.

Source : US National Library of Medicine

Studies on the efficacy of silver particles against microbial agents.

Treatment with silver leads to dehydration of microbial cells. A) Staphylococcus aureus without silver treatment as found on a catheter. B) Staphylococcus aureus on a silver-containing material with microdispersed silver particles throughout the matrix. Both images were captured using scanning electron microscopy. Notice the shrunken appearance of the cells (Guggenbichler et al., 1999).
The fluorescence microscopy and HRTEM images demonstrating the defective outer membrane/capsid in microbes caused due to silver treatment.

Polygiene is available from Gam Solutions in a convenient 100ml Spray and 100ml Wash-in Treatment.

©2024 GAM Solutions Pty Ltd ACN 144 542 941 | Hand and Surface Sanitizer | Fabric Sanitizer

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